Uvakalelo kunye neNgcaciso: Isixhobo sika-2019-nCOV/COVID-19 IgG/IgM Rapid Test Device sithelekiswe neRT-PCR ehamba phambili yovavanyo kusetyenziswa imizekelo yezonyango. Iziphumo zibonisa ukuba i-2019-nCoV/COVID-19 IgG/IgM Rapid Test Isixhobo sinovakalelo oluphezulu kunye nokukodwa.

Kuvavanyo lwe-IgG:

Uvakalelo olunxulumeneyo:233/268=86.94%(95%CI*:82.35%-90.49%)

Iinkcukacha Ngokuhambelanayo:287/289=99.31% (95%CI*:97.52%-99.92%)

Ukuchaneka:520/557=93.36% (95%CI*: 90.96%-95.16%)

*Ithuba lokuzithemba

Kuvavanyo lwe-IgM

Uvakalelo olunxulumeneyo:223/268=83.21% (95%CI*:78.19%-87.48%)

Iinkcukacha Ngokuhambelana:282/289=97.58% (95%CI*: 95.07%-99.02%)

Ukuchaneka: 505/557=90.66% (95%CI*: 87.94%-92.95%)

*Ithuba lokuzithemba

UMGAQO: Le khithi isebenzisa i-immunochromatography.Ikhadi lovavanyo liqulethe:1) igolide ye-colloidal-ibhalwe i-recombinant novel coronavirus antigen kunye nolawulo lomgangatho weempawu zegolide ze-antibody;2) imigca emibini yokubhaqa (imigca ye-IgG kunye ne-IgM) kunye nomgca woLawulo olusemgangathweni omnye (umgca C) we-nitrocellulose membrane. inoveli coronavirus I-antibody ye-IgM; umgca we-IgG awushukumi kunye ne-reagent yokukhangela inoveli coronavirus i-IgG antibody; kunye nomgca we-C ungenakunyakaziswa kunye ne-antibody yokulawula umgangatho.Xa isixa esifanelekileyo sesampuli yovavanyo yongezwa kwisampulu yomngxuma wekhadi lovavanyo, isampuli iya phambili kunye nekhadi lovavanyo phantsi kwesenzo se-capillary.Ukuba isampuli iqulethe i-antibody ye-IgM, i-antibody iya kubophelela kwigolide ye-colloidal-ibhalwe inoveli coronavirus antigen. I-immune complex iya kubanjwa yi-anti-IgM ye-antibody yomntu engashukumiyo kwi-membrane ukwenza umgca omfusa - obomvu we-IgM, ebonisa ukuba inoveli ye-coronavirus ye-IgM antibody ilungile. umgca, ebonisa ukuba inoveli coronavirus IgG antibody positive.Ukuba uvavanyo IgG kunye nemigca IgM ingenambala, isiphumo esibi sibonisiwe.Ikhadi lovavanyo liqulethe umgca wokulawula umgangatho we-C.Umgca wolawulo lwekhwalithi ye-fuchsia kufuneka uvele kungakhathaliseki ukuba umgca wovavanyo uvela.Umgca wokulawula umgangatho yibhanti yombala wokulawula umgangatho we-antibody immune complex. Ukuba umgca wokulawula umgangatho we-C awubonakali, umphumo wokuvavanya awusebenzi, kwaye isampuli kufuneka ihlolwe kwakhona kunye nelinye ikhadi lokuvavanya.

Nantsi into ekufuneka uyenzile ukuze uqhube uvavanyo:

1.Coca umnwe nge-alcohol swab.

2.Hlaba umnwe omnye ngepikha yomnwe ukufumana isampulu yegazi.

3.Ukukhulula isigqubuthelo senaliti jikela ngasekunene ulandele iintolo ezikwikhava.

4.Sebenzisa idropha ukutsala igazi ukuze ulifake kwikhasethi yovavanyo.

5.Khangela amanqaku kwikhasethi emva kwemizuzu eyi-10 ukuze ubone isiphumo.

ICoronavirus (CoV) yeyodidi lweNestovirus, Coronaviridae, kwaye yohlulwe yangamacandelo amathathu:α,β,kunye noγ.Intlobo α kunye ne-β zizifo ezanyisayo kuphela.I-genus γ ibangela ikakhulu usulelo lweentaka.I-CoV isasazwa ikakhulu ngokudibana ngqo nencindi okanye nge-aerosols namathontsi. Kukwakho nobungqina bokuba inokosulela ngendle/ngendlela yomlomo.

Ukuza kuthi ga ngoku, kukho iintlobo ezisi-7 ze-coronavirus yabantu (HCoV) ezibangela izifo zokuphefumla komntu: HCoV-229E,HCoV-OC43,SARS-CoV,HCoV-NL63,HCoV-HKU1,MERS-CoV kunye noveli coronaviruses (2019), yipathogen ebalulekileyo yosulelo lokuphefumla komntu.Phakathi kwayo, kwafunyaniswa i-coronavirus eyi-201 kwinoveli ziimpawu ezicwangcisiweyo ezifana nomkhuhlane kunye nokudinwa, okukhatshwa kukukhohlela okomileyo kunye ne-dyspnea, njl., enokuthi ikhule ngokukhawuleza ibe yinyumoniya enzima, ukungaphumeleli kokuphefumla, kunye nokuphefumla ngokukrakra.I-syndrome ye-Distress, i-septic shock, ukungaphumeleli kwamalungu amaninzi, i-asidi enzima-i-base metabolism disorders, njl. zinobomi-zisongela.

I-2019-nCOV/COVID-19 IgG/IgM Rapid Test Device luvavanyo olukhawulezayo lwechromatographic immunoassay ekubhaqweni komgangatho we-IgG&IgM antibody ye-Coronavirus Disease 2019 egazini lomntu lonke, serum, okanye iplasma njengoncedo ekufumaniseni usulelo lwe-COVID-19.