Chronic hepatitis B chirwere chakakomba, chinopedza simba chinogona kukonzera cirrhosis yechiropa, gomarara rechiropa uye rufu. Chronic hepatitis B ndiyo inonyanya kukonzera kenza yechiropa uye chegumi chinokonzera rufu munyika yose.Vanhu vakawanda vanorwisana nehutachiona ivo pachavo, asi inenge 5 - 10 muzana yeavo vane utachiona hwehutachiwana vanova vatakuri, uye imwezve 5 - 10 muzana yeavo vanotapukirwa gore negore vachafambira mberi kune chirwere chisingaperi chechiropa, cirrhosis uye zvichida kenza yechiropa.