【ISIFINYEZO】

Igciwane le-Hepatitis C (HCV) manje seliqashelwa njenge-ejenti enkulu ye-hepatitis engapheli, ukumpontshelwa okutholwa okungeyona-A,non-B isifo sokusha kwesibindi kanye nesifo sesibindi emhlabeni wonke.I-HCV iyigciwane le-RNA elihlanganisiwe, elilodwa-elihlanganisiwe. ukubonakaliswa kwama-antigen aphinde ahlanganiswe ezinhlelweni zebhaktheriya njenge-E.coli futhi egxile ezifundeni zesakhiwo nezingezona-zesakhiwo ze-HCV-i-polyprotein ekhodiwe, ayi-immunogenic nakanjani. Ama-antigens abalulekile avimbela amasosha omzimba alawa maprotheni abikwe njengabalulekile, i-NS3, NS4 kanye ne-NS5 yizifunda ezaziwa kakhulu ngaphansi kwe-HCV. Ukuze kuxilongwe ukutheleleka kwe-HCV, lawa maprotheni asetshenziswa njengezinto zokuthwebula zokuhlolwa kwe-immunochromatographic (okusheshayo). Uma kuqhathaniswa nokuhlolwa kwe-HCV yesizukulwane sokuqala kusetshenziswa ama-antigen aphinda ahlanganiswe, ama-antigen amaningi asebenzisa ama-recombinant proteins afakwe ekuhlolweni okusha kwe-serologic ukuze kugwenywe ukusebenza okungaqondile kwe-cross-umsebenzi kanye nokwandisa ukuzwela kwe-HCV komzimba.

【UKUZWAKALA】

I-recombinant antigen esetshenziselwa i-HCV Rapid Test Device (Serum/Plasma/Whole blood) ifakwe amakhodi wofuzo kukho kokubili amaprotheni esakhiwo (nucleocapsid) kanye nangewona-esakhiwo. I-HCV Rapid Test Device (Serum/Plasma/Whole blood) iphase iphaneli ye-seroconversion futhi yaqhathaniswa nokuhlolwa okuhamba phambili kwe-HCV EIA kusetshenziswa ama-clinical specimens. Imiphumela ibonisa ukuthi ukuzwela okuhlobene kwe-HCV Rapid Test Device(Serum/Plasma/Whole blood) kungu-99.99% futhi kucaciswe ngo-7%.